A Second Major Seasonal Virus Won’t Leave Us Any Choice

This pandemic will eventually be over, and the Delta surge—in which most of those not yet vaccinated against the coronavirus could become infected—may well be America’s last destructive wave. But just because we’re eager to move past the virus doesn’t mean it’s finished with us.

In our large, open, and globally connected society, getting to zero COVID, the , is as politically unrealistic as it is biologically implausible. Americans are mostly done with the onerous shutdowns that such a goal would require. The virus has now spread so widely in the world that even tight, long-lasting limits on Americans’ movement—restrictions far beyond what we would tolerate—could not stamp it out entirely. Instead, SARS-CoV-2 will become an endemic virus, settling alongside the other four strains of coronaviruses that circulate widely among