BBC Science Focus Magazine

Hungry all of the time? It could be in your blood

Nutritional scientist

WAS THERE A PARTICULAR REASON THAT BREAKFAST WAS THE MEAL YOU CHOSE TO FOCUS ON FOR THIS STUDY?

For the PREDICT study we had two components. One was a very tightly controlled clinic day where people were attending our clinic in the UK at St Thomas’s Hospital, or the clinic in the USA at Massachusetts General Hospital in Boston. And we gave them what we call a ‘metabolic challenge meal’ – a standardised, high-fat, highcarb meal for breakfast, in the form of a muffin and a milkshake. Then we gave them a standardised lunch to really stress their systems so we could start to differentiate people’s responses.

Then they entered a two-week at-home phase where they were fitted with This way we could also look in a very real-life context, as well as in this tightly controlled context.

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