NPR

Vaccine Makers Hedge Bets On Which One Will Emerge As Effective And Safe

To speed vaccine production from years to months, companies must start making a vaccine in large quantities even before it's clear a vaccine works.
Cell culture operators prepare a 2000-liter single-use bioreactor to produce proteins used to make vaccines.

Once upon a time, developing a new vaccine was a step-by-step process that went from concept, to design, to tests in humans, to regulatory approval, to manufacturing.

It was a process that could take a decade or more.

But the urgent need for a COVID-19 vaccine has radically changed all that. Now, the hope is the entire process can be completed in a year or less.

A good example of the new paradigm is a. It's what's called a protein subunit vaccine. The proteins are encased in a nanoparticle that gets injected into a person, along with a generalized immune stimulant known as an adjuvant.

You’re reading a preview, subscribe to read more.

More from NPR

NPR3 min read
Taiwan's New President Urges China To Stop Its Military Intimidation
Taiwan's new President Lai Ching-te in his inauguration speech has urged China to stop its military intimidation against the self-governed island Beijing claims as its own territory.
NPR2 min readCrime & Violence
How Does Trump's Trial End? It May Hinge On How Jurors Feel About Sex And Privacy
The Trump's Trials team breaks down why prosecutors have a timeline problem, what Michael Cohen's testimony so far has shown, and why it may all come down to a question of sex and privacy in the end.
NPR3 min read
In Knesset Speech, GOP's Elise Stefanik Calls For Unrestricted U.S. War Aid To Israel
Stefanik spoke before a caucus of Israel's parliament focused on antisemitism on college campuses around the world. She called for Hamas to be wiped "off the face of the earth."

Related Books & Audiobooks