STAT

Opinion: Did a high-profile program really slash hospital spending? Or was it a cautionary tale of ‘regression to the mean’?

Regression to the mean is a concern for studies of health care programs that are often implemented in response to extreme signals like advanced disease, high expenditures, or excessive prescribing.

In the late 19th century, English polymath Sir Francis Galton noted that tall parents often had kids shorter than they were, while short parents often ended up with taller kids. He dubbed this regression to the mean — when something measured as extreme in a first instance is likely to be measured as less extreme later on.

That concept has important implications for health care policy today, one of which is that more health policymakers and health care researchers should use randomized evaluations to avoid problems of regression to the mean in estimating the effects of policies.

In the U.S. health care system, the very highest-cost patients — known as super-utilizers — have

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