The Atlantic

It’s Possible to Inherit More DNA From One Parent Than the Other

23andMe’s 4-million-person database reveals how many people are living with undetected chromosomal anomalies.
Source: Alain Nogues / Getty

Updated at 10:52 a.m. on October 11, 2019.

Before Natalie Nakles was born, before the egg from which she was conceived was even fully mature, something went slightly awry. The egg that would help form her ended up with two copies of chromosome 16. So today, 24-year-old Nakles does not, as most people do, have one set of chromosomes from each parent. She has two copies of chromosome 16 from her mother and none from her father.

This phenomenon, called uniparental disomy, can happen in any of the 23 pairs of chromosomes. In

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