NPR

Genetically Modified Viruses Help Save A Patient With A 'Superbug' Infection

Treatment with genetically altered bacteriophages — viruses that attack bacteria — may have halted a patient's near-fatal infection, hinting at new ways to fight antibiotic-resistant bacteria.
Isabelle Carnell-Holdaway (left), now 17, with her mother Joanne Carnell-Holdaway. Isabelle has a dangerous infection that is being treated with a cocktail of genetically modified viruses.

For the first time, scientists have used genetically modified viruses to treat a patient fighting an antibiotic-resistant infection.

Isabelle Carnell-Holdaway, 17, began the experimental treatment after doctors lost all hope. She was struggling with a life-threatening infection after a lung transplant. With the new treatment, she has not been completely cured. But the Faversham, England, teenager has recovered so much that she has resumed a near-normal life.

"I think it's amazing," Carnell-Holdaway says. "It kind of shows that there is completely no limit to what they can come up with really."

Doctors and scientists stress that it's difficult to

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