NPR

Search Of DNA In Dogs, Mice And People Finds 4 Genes Linked To OCD

Scientists looking for genetic factors behind obsessive compulsive disorder looked for clues in the DNA of humans and two animal species. Genes active in a particular brain circuit emerged.
Dogs may not wash their paws compulsively, but some humans and canines have similar genetic mutations that may influence obsessive behavior.

People who have obsessive-compulsive disorder can get trapped inside a thought. It repeats itself, like a stuck song. Did I lock the door? Is that doorknob is clean enough to touch? I better wash my hands again – and again.

The biology underpinning this loop remains murky to scientists, but scientists are beginning to sniff out potential genetic factors behind OCD and shed light on how the disorder affects the brain.

Research Tuesday in identifies four genes, a senior author on the study and a geneticist at the Broad Institute of MIT and Harvard University.

You’re reading a preview, subscribe to read more.

More from NPR

NPR2 min readCrime & Violence
Guatemalan AG Raids Save The Children Office Over A Migrant Children Rights Complaint
Prosecutor Rafael Curruchiche said that the complaint filed by an unidentified foreigner had raised serious concerns because it involved allegations of abuse of children.
NPR3 min readAmerican Government
Trump's Immunity Arguments And The Experiences Of The Justices Who Might Support It
Five of the six conservatives spent much of their lives in the Beltway, working in the White House and Justice Department, seeing their administrations as targets of unfair harassment by Democrats.
NPR7 min read
As Bird Flu Spreads In Cows, Here Are 4 Big Questions Scientists Are Trying To Answer
Health officials say there's very little risk to humans from the bird flu outbreak among dairy cattle, but there's still much they don't know. Here are four questions scientists are trying to answer.

Related Books & Audiobooks