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How We Got From Doc Brown to Walter White

At the start of the fourth season of Breaking Bad, Walter White angrily watches an inexperienced meth cook make his trademark blue meth. Walter is afraid that mob boss Gus Fring is going to kill him, so he desperately explains that Fring can’t make the “product” without him. When the amateur cook, Victor, says he knows every step of the process, Walter snarls, “So, please, tell me. Catalytic hydrogenation—is it protic or aprotic? Because I forget. And if our reduction is not stereospecific, then how can our product be enantiomerically pure?”

Walter’s scientific knowledge saves him. The ruthless Fring slits Victor’s throat with a box cutter.

Over the course of Breaking Bad, Walter unravels from a frustrated chemistry teacher to a brutal criminal. But no matter how horrible he gets, viewers can’t help but relate to and care about him. Much of this sense of connection comes from lead actor Bryan Cranston’s skillful portrayal of a troubled family man, but it was Breaking Bad creator and head writer Vince Gilligan who conceived the character. He imagined a scientist who is mad without turning him into a mad scientist.

CHEMICAL BURN: In a tense Breaking Bad scene, Walter White taunts Gus Fring’s meth cook Victor to answer his question: “I mean, it’s 1-Phenyl-1-Hydroxy-2-Methylaminopropane, containing, of course, chiral centers at carbon numbers 1 and 2 on the propane chain. Then reduction to methamphetamine eliminates which chiral center is it again?”Courtesy of AMC

Part of Walter’s appeal is he knows his science. “Vince tried to get the chemistry correct as much as he could, just to make it more believable,” says Donna Nelson, a professor of chemistry at the University of Oklahoma. As ’s science advisor, Nelson helped him achieve that goal. (Her favorite scene in the series is Walter’s sarcastic rejoinder to Victor.) Although they were careful to never give viewers the exact or complete recipe for meth, the chemical reactions are real, and if someone were to synthesize methamphetamine by altering other chemical’s structures, they would indeed want to

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