Stem Cell Innovation in Health & Disease Series
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About this series
Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases.
- Provides cutting-edge research needed to understand stem cell functions in joint and bone diseases
- Develops processes to bring stem cells from bench to bedside
- Includes up-to-date references on stem cell biology and function in the joint and bone
Titles in the series (4)
- The Eye
4
The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics. Provides cutting-edge research to understand stem cell functions used in disease treatments of the eye Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in common eye diseases and disorders
- The Lung
In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the lung
- The Intestine
The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the intestine
- Joint and Bone: From Bench to Bedside
Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside. Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases. Provides cutting-edge research needed to understand stem cell functions in joint and bone diseases Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in the joint and bone
Ahmed El-Hashash
Dr. El-Hashash is a fellow of the California Institute of Regenerative Medicine and New York University Medical School. Prof. El-Hashash worked as a senior biomedical research scientist at Mount Sinai School of Medicine of New York University and Children’s Hospital Los Angeles. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at Keck School of Medicine and Ostrow School of Dentistry of The University of Southern California. In 2016, Prof. El-Hashash joined The University of Edinburgh, Edinburgh Medical School-Zhejiang International Campus, as Tenure-Track Associate Professor and Senior Principal Investigator of Biomedicine, Stem Cell & Regenerative Medicine. Prof. El-Hashash has several breakthrough discoveries in genes/enzymes that control stem cell behavior and regenerative medicine and has published more than 25 papers in international journals and serves as an editorial board member of repute. He is the editor or author of several books on stem cell and regenerative medicine.
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