Recent Results in Cancer Research Series
By Uwe M. Martens and Michail Ignatiadis
()
About this series
This book presents in detail the problems and ethical challenges in daily oncological practice.
In western industrialized countries, roughly 25 percent of all citizens still die from cancer. Despite significant progress in basic science and in individual areas of clinical care, even in the 21st century, being diagnosed with cancer has lost none of its dread and can still be a death sentence. This situation raises many problems and challenges for medical ethics, e.g., the question of the benefits and risks of prevention programs, or the right to know and not to know.
Clinical trials with cancer patients and quality assurance for surgery, radiotherapy and medication also pose a series of ethical dilemmas. Furthermore, cancer treatment is a psychological challenge not only for patients but also for physicians and caregivers. The issues of adequate pain management and good palliative care, of treatment limiting and the question of assisted suicide at the end of life also have to be considered. In order to reflect the subject’s diverse and multifaceted nature, the book incorporates legal, ethnographic, historical and literary perspectives into ethical considerations.
Titles in the series (5)
- Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer
195
This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.
- Small Molecules in Oncology
211
This book, written by respected experts, discusses in detail the latest developments in targeted oncology therapy using small molecules. It covers a wide range of small molecules, including tyrosine kinase inhibitors, mTOR, MEK, PARP, and multikinase inhibitors, as well as cell cycle and NTRK interacting agents. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the advances being made will mean significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book is the third edition of Small Molecules in Oncology, but has now been divided into two volumes, with the other volume focusing specifically on small molecules in hematology.
- Small Molecules in Hematology
212
This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of precision cancer therapy is now growing rapidly, and the advances being made will mean significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. An accompanying volume addresses the use of small molecules in oncology, and the two volumes together represent the third edition of the book originally published under the same title.
- Tumor Liquid Biopsies
215
This book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted proteomics. The use of such advanced technologies is enabling us to tackle questions and problems in a way that was not possible just a few years ago. We now have at our disposal an effective means of overcoming the problem of intratumor heterogeneity, which has limited the value of conventional biopsy approaches. As a consequence, oncology practice is about to change radically, toward truly personalized precision medicine. This book provides both clinicians and researchers with a thorough and up-to-date overview of progress in the field.
- Ethical Challenges in Cancer Diagnosis and Therapy
218
This book presents in detail the problems and ethical challenges in daily oncological practice. In western industrialized countries, roughly 25 percent of all citizens still die from cancer. Despite significant progress in basic science and in individual areas of clinical care, even in the 21st century, being diagnosed with cancer has lost none of its dread and can still be a death sentence. This situation raises many problems and challenges for medical ethics, e.g., the question of the benefits and risks of prevention programs, or the right to know and not to know. Clinical trials with cancer patients and quality assurance for surgery, radiotherapy and medication also pose a series of ethical dilemmas. Furthermore, cancer treatment is a psychological challenge not only for patients but also for physicians and caregivers. The issues of adequate pain management and good palliative care, of treatment limiting and the question of assisted suicide at the end of life also have to be considered. In order to reflect the subject’s diverse and multifaceted nature, the book incorporates legal, ethnographic, historical and literary perspectives into ethical considerations.
Related to Recent Results in Cancer Research
Related ebooks
Flying Saucers Vs. the Earth #1 Rating: 0 out of 5 stars0 ratingsThe Man in the Mirror Journal: Everything Begins and Ends with You Rating: 0 out of 5 stars0 ratingsPolitical Power: Portrait Gallery Rating: 0 out of 5 stars0 ratingsLittle Bigfoot Rating: 0 out of 5 stars0 ratingsSweet Pea Saves the Rainbows Rating: 0 out of 5 stars0 ratingsSpecial and Different: The Autistic Traveler: Judgment, Redemption, & Victory Rating: 0 out of 5 stars0 ratingsKyron and The Meadow Monster Rating: 0 out of 5 stars0 ratingsVincent Price Presents: Tinglers Rating: 0 out of 5 stars0 ratingsI Rescued Two Dogs: Now Who Will Rescue Me? Rating: 0 out of 5 stars0 ratingsFinding Treasured Gold Rating: 0 out of 5 stars0 ratingsFabulous Beekman Boys Present: Polka Spot #3 Rating: 0 out of 5 stars0 ratingsTom Corbett: Space Cadet: Classic Edition #8 Rating: 0 out of 5 stars0 ratingsPolitical Power: Ted Kennedy Rating: 0 out of 5 stars0 ratingsColonial Comics: New England: 1620 - 1750 Rating: 4 out of 5 stars4/5Isfjell Point Rating: 0 out of 5 stars0 ratingsLazar & Jingles and Bunson in Holiday Gifts Rating: 0 out of 5 stars0 ratingsTails of Wisdom: Lessons I Learned from My Dogs Rating: 0 out of 5 stars0 ratingsGrowing Up on the Farm Rating: 0 out of 5 stars0 ratingsLogan's Run: Aftermath Rating: 0 out of 5 stars0 ratingsGabriel: The Shattered Star Rating: 0 out of 5 stars0 ratingsGLO Workbooks Great Learning Opportunity Rating: 0 out of 5 stars0 ratingsOdyssey Presents: Anthology #1 Rating: 0 out of 5 stars0 ratingsA Caboodle of Cat Tales Rating: 0 out of 5 stars0 ratingsAdventures with Oakie the Other Heroes Rating: 0 out of 5 stars0 ratingsOn the Way Rating: 0 out of 5 stars0 ratingsTrapped in the Tower Rating: 0 out of 5 stars0 ratingsFemale Force: Gabrielle Giffords Rating: 0 out of 5 stars0 ratingsJustly Poetic Rating: 0 out of 5 stars0 ratingsMud Pups’ Adventures vol. 1 Rating: 0 out of 5 stars0 ratingsTill Death Us Do Part Rating: 0 out of 5 stars0 ratings
Medical For You
Mediterranean Diet Meal Prep Cookbook: Easy And Healthy Recipes You Can Meal Prep For The Week Rating: 5 out of 5 stars5/5Mating in Captivity: Unlocking Erotic Intelligence Rating: 4 out of 5 stars4/5The 40 Day Dopamine Fast Rating: 4 out of 5 stars4/5Tight Hip Twisted Core: The Key To Unresolved Pain Rating: 4 out of 5 stars4/5The Diabetes Code: Prevent and Reverse Type 2 Diabetes Naturally Rating: 4 out of 5 stars4/5Period Power: Harness Your Hormones and Get Your Cycle Working For You Rating: 4 out of 5 stars4/5Adult ADHD: How to Succeed as a Hunter in a Farmer's World Rating: 4 out of 5 stars4/5Living Daily With Adult ADD or ADHD: 365 Tips o the Day Rating: 5 out of 5 stars5/5The Vagina Bible: The Vulva and the Vagina: Separating the Myth from the Medicine Rating: 5 out of 5 stars5/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5Healthy Gut, Healthy You: The Personalized Plan to Transform Your Health from the Inside Out Rating: 4 out of 5 stars4/5What Happened to You?: Conversations on Trauma, Resilience, and Healing Rating: 4 out of 5 stars4/5Holistic Herbal: A Safe and Practical Guide to Making and Using Herbal Remedies Rating: 4 out of 5 stars4/5WomanCode: Perfect Your Cycle, Amplify Your Fertility, Supercharge Your Sex Drive, and Become a Power Source Rating: 4 out of 5 stars4/5Women With Attention Deficit Disorder: Embrace Your Differences and Transform Your Life Rating: 5 out of 5 stars5/5The Amazing Liver and Gallbladder Flush Rating: 5 out of 5 stars5/5ATOMIC HABITS:: How to Disagree With Your Brain so You Can Break Bad Habits and End Negative Thinking Rating: 5 out of 5 stars5/5Herbal Healing for Women Rating: 4 out of 5 stars4/5Working Stiff: Two Years, 262 Bodies, and the Making of a Medical Examiner Rating: 4 out of 5 stars4/5Woman: An Intimate Geography Rating: 4 out of 5 stars4/5Unhinged: The Trouble with Psychiatry - A Doctor's Revelations about a Profession in Crisis Rating: 4 out of 5 stars4/5The Art of Dying Well: A Practical Guide to a Good End of Life Rating: 4 out of 5 stars4/5"Cause Unknown": The Epidemic of Sudden Deaths in 2021 & 2022 Rating: 5 out of 5 stars5/5
Related categories
Reviews for Recent Results in Cancer Research
0 ratings0 reviews