Protides of the Biological Fluids Series

Protides of the Biological Fluids: An International Review Series Devoted to Proteins and Related Studies, Volume 29: Membrane Proteins, Receptor Ligand Interactions, Monoclonal Antibodies, New Methods focuses on membrane proteins, receptor-ligand interactions, and monoclonal proteins as a reagent. The selection first offers information on H-Y and sex determination and aspects of the difficulties to purify membrane proteins. Topics include solubilization by acylation, influence of supporting media on the aggregation of proteins, solubilization with detergents and organic solvents, and membrane proteins - giant detergent molecules. The text then examines the application of group-specific reagents for hydrophobic labeling and crosslinking of membrane proteins and comparison of secreted and membrane-bound human immunoglobulins M and D. The publication tackles sialoglycoproteins (glycophorins) in the plasma membranes of different cells and their receptor functions and the structures and antigenic properties of human erythrocyte membrane sialoglycoproteins. Discussions focus on the primary structure of human erythrocyte glycophorins, molecular structure of the MN bloodgroup substance, and genetic variants of glycophorin A. The book also takes a look at the glycoproteins of the human syncytiotrophoblastic plasma membrane and structure and function of a membrane glycoprotein encoded in the adenovirus genome. The selection is a valuable reference for readers interested in membrane proteins, receptor ligand interactions, and monoclonal antibodies.

Protides of the Biological Fluids: Proceedings of the 30th Colloquium, 1982 is a collection of manuscripts presented at the 30th Colloquium, held in Brussels, Belgium in 1982. This text is organized into three sections encompassing 160 chapters. The first section highlights the mechanisms of the normal and abnormal mental function through evaluation of neuroproteins or the so-called “think-proteins. This section describes the manifestations, clinical features, diagnosis, and therapeutic options of nervous system diseases. The second section tackles monoclonal proteins as a reagent to detect antigens. This section deals with the significant progress in cancer therapy and the binding of cytotoxic drugs to monoclonal antibodies. The third section considers the potential of isodalt electrophoresis and high-pressure liquid chromatography, with particular emphasis on their application to protein analysis in biological fluids. This book will be of great value to biochemists, clinical chemists, and clinicians.

Protides of the Biological Fluids: Metal Binding Proteins, Tumor Markers, Monoclonal Antibodies covers the proceedings of the 31st Colloquium by the same title, held in Brussels, Belgium in 1983. This work is composed of three sections encompassing 245 chapters. The first section describes first the structure, physiological function, and physiopathology of metal binding proteins. This section also considers the metal binding mechanism and a series of iron binding and copper binding proteins, as well as hemopexin proteins. The second section is concerned with the physiopathology, screening, monitoring, tumor localization, and biomarkers of tumor. This section also explores the field of immunohistochemistry of biomarkers for tumor monitoring. The third section discusses drug targeting, immunohistochemistry, the identification of lymphocytes and other antigens. Considerable chapters are devoted to clinical assays of monoclonal antibodies. This book will prove useful to oncologists, protein scientists, clinicians, and researchers.

An International Review Series Devoted to Proteins and Related Studies, Volume 32: Protides of the Biological Fluids documents the proceedings of the 32nd Colloquium held in 1984. This compilation is organized into three parts. Part I begins with an introduction to the defense mechanism of immunoglobulins, followed by a description of enzymes and proteins, such as lactoperoxidase and lactoferrin. The secretions that include CSF, colostrum, milk, female and male genital secretions, saliva, gastrointestinal juice, nasal and bronchoalveolar secretions, tears and synovial fluid are also elaborated. The tumor markers, which include ferritin, CEA, and TPA are dealt with in Part II. The immunotoxins, tumor imaging, and lymphoid malignancies are also covered. Part III is devoted to the advances in the separation of protides, including the staining procedure for protein detection, two-dimensional electrophoresis, and HPLC and affinity chromatography. This book is valuable to biology students and clinicians of disciplines related to advances in the protein field.

An International Review Series Devoted to Proteins and Related Studies, Volume 33: Protides of the Biological Fluids documents the proceedings of the 33rd Colloquium held in 1985. This book is divided into three sections. Section A focuses on the plasma protein genes that includes the location of genes on the chromosome, pathology and variance of several genes, and gene expression. The proteins of the nucleus and detection of antibodies, such as antinuclear antibodies (ANA), to nuclear constituents are deliberated in Section B. Section C is devoted to the technical advances in the field of protein chemistry. This book is a good reference for students, researchers, and medical practitioners conducting work on the protides of biological fluids.