Public health agencies work around the clock to prepare for and respond to public health threats, including infectious diseases, natural disasters, clinical care emergencies, and more. While advanced preparedness planning is invaluable, past and current emergencies also serve as critical learning opportunities to inform future public health responses. In this episode, Haley Cash (Pacific Island Health Officers Association) and Secretary Jack Niedenthal (Republic of the Marshall Islands) share insights into the unique strategies and successes of COVID-19 responses in the U.S.-Affiliated Pacific Islands. How have these jurisdictions—with unique needs and oftentimes limited supplies—managed to protect their populations over the last two years? Our experts dive into key lessons and share broader takeaways for future public health crises. Resources: USAPI COVID-19 Response Hub ASTHO JPHMP Article: US-Affiliated Pacific Islands Response to COVID-19: Keys to Success and Important Lessons ASTHO Newscast Clip: Fighting COVID-19 in the Pacific ASTHO Blog: Reflections From the Field: Pacific and Atlantic Jurisdictions Remain Resolute Amid Adversity