Sporting News' Vinnie Iyer breaks down the best targets for the Week 6 waiver wire in the wake of red-hot Dolphins rookie running back De'Von Achane (knee) and Vikings wide receiver Justin Jefferson (hamstring) set to miss multiple games, right along with Colts quarterback Anthony Richardson. While the Bears (Roschon Johnson), the Cardinals (Emari Demarcado) and Titans (Tyjae Spears) might help the RB-needy, look first to K.J. Osborn right in Minnesota for a WR boost. Also, there are good streaming options at QB, TE, and defense to target per usual.Support Us By Supporting Our Sponsors!Jase MedicalSave more than $360 by getting these lifesaving antibiotics with Jase Medical plus an additional $20 off by using code LOCKEDON at checkout on jasemedical.com.PrizePicksGo to PrizePicks.com/lockedonnfl and use code lockedonnfl for a first deposit match up to $100!GametimeDownload the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Last minute tickets. Lowest Price. Guaranteed.eBay MotorsFor parts that fit, head to eBay Motors and look for the green check. Stay in the game with eBay Guaranteed Fit at eBayMotos.com. Let’s ride. eBay Guaranteed Fit only available to US customers. Eligible items only. Exclusions apply.LinkedInLinkedIn Jobs helps you find the qualified candidates you want to talk to, faster. Post your job for free at LinkedIn.com/LOCKEDONNFL. Terms and conditions apply.FanDuelMake Every Moment More. Right now, NEW customers can bet FIVE DOLLARS and get TWO HUNDRED in BONUS BETS – GUARANTEED. Visit FanDuel.com/LOCKEDON to get started.FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Learn more about your ad choices. Visit podcastchoices.com/adchoices