Preprint servers and professional discourse on social media sites like Twitter have been incredibly helpful in spreading useful information as the COVID-19 pandemic changes over time. But they clearly function as a double-edged sword, spreading information rapidly prior to traditional peer review. JAMA Network Open Editors Eli Perencevich, MD, MS and Roy Perlis, MD, MSc join us to discuss on JNOLive. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.