In this episode, host Dr. Jose Silva and Dr. Padraic O’Malley, a urologic oncologist from University of Florida Health, discuss how to diagnose and treat upper tract urothelial carcinoma.

Referencing official guidelines and personal experiences, the doctors discuss various treatments such as tumor ablation, JELMYTO, neoadjuvant chemotherapy, and nephroureterectomy. They also discuss the role of lymph node dissection and the significance of Lynch syndrome. Additionally, they touch upon the Thulium laser and updated staging guidelines. The episode concludes with discussions about follow-up care, and the doctors agree on the need for a standardized reporting system and risk stratification guidelines for improved patient management.

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SHOW NOTES

00:00 - Introduction
02:09 - Initial Presentation of Patients with Upper Tract Urothelial Carcinoma
10:54 - Discussion on Lynch Syndrome
14:27 - Risk Stratification in Patients
15:37 - Tumor Ablation and Intracavitary Therapies
26:47 - The Use of Thulium Laser in Treatment
28:50 - Discussion on High Volume Disease
32:39 - Discussion on High Grade Tumors
38:23 - The Role of Neoadjuvant Chemotherapy
43:02 - Post-Treatment Follow Up
45:18 - Standardized Reporting in Guidelines