Dr. Francis Deng summarizes major highlights of current research and future trends from the September 2023 Neuroradiology Centennial content. Functional MRI in Neuro-Oncology: State of the Art and Future Directions. Pasquini et al. Radiology 2023; 308(3):e222028. Neuroimaging in Dementia: More than Typical Alzheimer Disease. Haller et al. Radiology 2023; 308(3):e230173. MRI of the Brain: What Is Driving Innovation in 2023? Hess. Radiology 2023; 308(3):e231657.  Challenges of Preparing for Diagnostic Radiology Call. Isikbay et al. Radiology 2023; 308(3):e230421. Neurochemical Differences between 1p/19q Codeleted and Noncodeleted IDH-mutant Gliomas by in Vivo MR Spectroscopy. Branzoli et al. Radiology 2023; 308(3):e223255. Correlating Quantitative MRI-based Apparent Diffusion Coefficient Metrics with 24-month Neurodevelopmental Outcomes in Neonates from the HEAL Trial. Calabrese et al. Radiology 2023; 308(3):e223262.