There’s something powerful about the sound of a scream. Whether it pierces the silence of an empty building or rings out through a crowded room, it forces you to stop what you’re doing and take note. It turns out there’s a scientific explanation for that. Our brains are hardwired to recognize the sound of a human scream as a distress signal so that we can respond accordingly. We talked to neuroscientist Luc Arnal about what particular sounds make a scream a scream and how he studies the brain circuits that interpret them. This episode was produced by Andrew Saintsing and mixed by Collin Warren.