Peter Hotez is a professor in the Departments of Pediatrics and Molecular Virology and Microbiology and dean of the National School of Tropical Medicine at Baylor College of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P.J. Hotez and A.D. LaBeaud. Yellow Jack’s Potential Return to the American South. N Engl J Med 2023;389:1445-1447.