Freeze fracture is a powerful technique that enables imaging of internal structures of cells and tissues at the nanoscale level by freezing samples at ultra-low temperatures and then fracturing them along natural weak points. These structures can be imaged without dehydration or distortion using cryo-SEM, providing high-resolution images with great clarity.Discover how to use freeze fracture and cryo-SEM workflow to answer research questions and learn its exciting applications in cell biology.Watch the full presentation here: https://microscopyfocus.com/breaking-the-ice-freeze-fracture/Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/