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Omidubicel vs standard umbilical cord blood transplant, CAR T-cell associated lymphomas, and CD63 and ferritin export
FromBlood Podcast
Omidubicel vs standard umbilical cord blood transplant, CAR T-cell associated lymphomas, and CD63 and ferritin export
FromBlood Podcast
ratings:
Length:
20 minutes
Released:
Oct 21, 2021
Format:
Podcast episode
Description
In this week’s episode, we’ll review results of a phase 3 randomized study demonstrating shorter time to neutrophil and platelet recovery with an ex vivo expanded hematopoietic progenitor cell product called omidubicel as compared to standard umbilical cord transplantation. Next, we’ll look at preliminary data on the development of lymphomas originating from piggyBac-modified CD19 CAR T-cells, sounding a note of caution for researchers exploring new gene modification methodologies for CAR T-cell production. We’ll conclude with a report suggesting that the vesicular protein CD63 may orchestrate the transfer of iron-rich ferritin among cells.
Released:
Oct 21, 2021
Format:
Podcast episode
Titles in the series (100)
Blood Podcast - Trailer: This is a trailer for the Blood Podcast, a podcast series that will provide timely information about research published in Blood, the most cited peer-reviewed publication in the field of hematology. Each episode will provide a summary of recent Blood arti by Blood Podcast