For a generation growing up in the rural US state of Virginia, opioid addiction isn't an abstraction - it's neighbours, parents, and friends.   Writer Barbara Kingsolver wanted to give these ‘lost boys’ of Appalachia a voice; to tell the story of the children forced into a life of foster care because their parents are dead, in prison or too incapacitated by addiction.   Today on Ways to Change the World, the award-winning author joins Krishnan Guru-Murthy to talk about America’s opioid crisis, the devastating impact it has on rural communities and how she set out to write ‘the great Appalachian novel’, tracing back the steps of Charles Dickens.   Produced by Silvia Maresca