When fluid resuscitating a hypotensive patients, how do you know when to continue with IV fluids and when to initiate vasopressors? In this episode, critical care teaching legend Nicole Kupchik, RN MSN CNS, shares evidence-based practices for determining the best course of action. Explore the significance of noninvasive measurements in assessing fluid responsiveness and learn how incorrect decisions can lead to adverse patient outcomes. Nicole Kupchik's latest book, The Critical Care Survival Guide, is a concise bedside reference book with easy-to-access resources for anyone working in critical care regardless of experience level.Studies that support the use of balanced crystalloids in fluid resuscitation versus normal saline:Balanced Crystalloids versus Normal Saline in Adults with Sepsis: A Comprehensive Systematic Review and Meta-AnalysisLactated Ringer's Solution Reduces Systemic Inflammation Compared With Saline in Patients With Acute Pancreatitis