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AI identifies gene interactions to speed up search for treatment targets

AI identifies gene interactions to speed up search for treatment targets

FromNature Podcast


AI identifies gene interactions to speed up search for treatment targets

FromNature Podcast

ratings:
Length:
21 minutes
Released:
May 31, 2023
Format:
Podcast episode

Description

In this episode:00:46 An AI that predicts gene interactionsMapping the network of genes that control cellular processes can be difficult to do when gene-expression data is sparse, such as in rare diseases or those affecting tissues that are hard to clinically sample. To overcome this, a team has developed an artificial intelligence system trained on a large, general dataset, and used it to make predictions about gene interactions in data-limited situations. As a test-case they look at the heart condition cardiomyopathy, and show that the system can identify potential interactions that could represent new therapeutic targets.Research article: Theodoris et al.09:08 Research HighlightsMicrobes that can break down persistent ‘forever chemicals’, and why intermolecular distances are the key to keeping gummy sweets chewy.Research Highlight: Microbes take the ‘forever’ out of ‘forever chemicals’Research Highlight: Better gummy sweets are within reach, thanks to physics12:06 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, how chronic stress can inflame the gut, and understanding how rocket launches might impact wildlife.Nature News: Chronic stress can inflame the gut — now scientists know whyNature News: Does the roar of rocket launches harm wildlife? These scientists seek answersSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.
Released:
May 31, 2023
Format:
Podcast episode

Titles in the series (100)

The Nature Podcast brings you the best stories from the world of science each week. We cover everything from astronomy to zoology, highlighting the most exciting research from each issue of Nature journal. We meet the scientists behind the results and providing in-depth analysis from Nature's journalists and editors.