Former CDC Executive Secretariat of the Advisory Committee on Immunization Practices Amanda Cohn, MD, joins JAMA Associate Editor Preeti Malani, MD, for the latest on the need for vaccination and boosters, vaccine misinformation, and tackling the pandemic from a global perspective. Recorded January 6, 2022. Related Content: One Year of COVID-19 Vaccines: A Shot of Hope, a Dose of Reality COVID-19 Vaccines Have Been Available in the US for More Than a Year—What’s Been Learned and What’s Next? COVID-19 CDC Update – Early January 2022