The lifting of the COVID-19 public health emergency (PHE) at the federal level will have significant impact on clinical, public health and research in infectious diseases beyond. In this episode, director of health for the city of St. Louis Mati Hlatshwayo Davis, MD, MPH is joined by Allison Agwu, MD, ScM, FIDSA and Maximo Brito, MD, MPH, FIDSA to discuss the urgency for prioritizing health equity beyond the COVID-19 Emergency Order Conclusion.