Chronicling a Trailblazer of the Genomics Age

FromThe Bio Report

Start listening View podcast show

Chronicling a Trailblazer of the Genomics Age

FromThe Bio Report

ratings:

Length:

23 minutes

Released:

Aug 18, 2016

Format:

Podcast episode

Description

Lee Hood was a visionary who helped enable the genomics age. Journalist Luke Timmerman, in his newly published biography of Hood, chronicles the scientist career and achievements, as well as the controversies that surrounded him. We spoke to Timmerman about Hood, the conflicts that shaped his career, and the significance of his contributions to the field of biology.

Released:

Aug 18, 2016

Format:

Podcast episode

Titles in the series (100)

The Bio Report podcast, hosted by award-winning journalist Daniel Levine, focuses on the intersection of biotechnology with business, science, and policy.

Skip carousel

International Collaboration Seeks to Drive Breakthroughs in Progressive MS: There has been dramatic progress in the understanding and treatment of relapsing remitting multiple sclerosis, a debilitating neurodegenerative disorder. But progressive MS, a more advanced form of the disease, has remained elusive. Now, a novel coll... by The Bio Report
24 min listen
How New Funding Models Are Accelerating Drug Development: News last month of the Cystic Fibrosis Foundation’s $3.3 billion sale of royalty rights to Kalydeco and other Vertex Pharmaceuticals drugs it helped fund served as a bold statement to the growing prominence and power of venture philanthropy. We spok... by The Bio Report
18 min listen
Democratizing the World of Healthcare Analytics: There’s no shortage of data created in the world of healthcare, but harnessing it to improve care and reduce costs remains a challenge. Apervita, backed with $18 million recent venture investment from GE Ventures, Baird Capital, and others is a mark... by The Bio Report
19 min listen
Moving from Chronic Therapies to Cures: The rapidly growing area of regenerative medicine is promising to replace chronic therapies with cures. As the biotechnology industry gathers in San Francisco for a big week of meetings, the Alliance for Regenerative Medicine is readying to deliver i... by The Bio Report
22 min listen
Remembering Industry Pioneer Ron Cape by The Bio Report
27 min listen
What’s Driving the Booming Market for Orphan Drugs: The market for Orphan drugs is growing at more than twice the rate of other prescription medicines In 2013, a record 260 therapeutics won orphan designations in the United States alone as science, policy, and pricing are fueling the trend for drugmak... by The Bio Report
18 min listen
The Forces Bringing Disruptive Change to Healthcare: Scientific breakthroughs, innovations in technology, and the changing use of data are among the forces that are driving disruptive changes to healthcare. A new report from the IMS Institute for Healthcare Informatics highlights a number of these deve... by The Bio Report
21 min listen
Epirus Sees Opportunities for Biosimilars Outside U.S.: The regulatory pathway for biosimilars is still a work in progress at the U.S. Food and Drug Administration, but around the world the industry is growing as regulators have resolved issues that remain obstacles in the United States. We spoke to Amit ... by The Bio Report
18 min listen
Using Human Biology to Improve R&D: One problem with drug discovery and development is that answers about the way substances act in the human body are often not apparent early in the process. Though human cell assays have been used, they have their limitations. BioSeek’s BioMap technol... by The Bio Report
28 min listen
Brittany Maynard and the Debate over the Right to Die: Brittany Maynard, a 29-year-old woman with terminal brain cancer who chose to end her own life with a lethal dose of medication, sparked a renewed discussion of so-called death with dignity laws. Maynard had become visible on social and traditional m... by The Bio Report
23 min listen
How One Foundation is Getting the Biggest Bang for Its R&D Bucks: As pressure on government and corporate research budgets grow, organizations like the Multiple Myeloma Research Foundation are playing an increasingly critical role in advancing and accelerating drug development. The foundation’s efforts, including i... by The Bio Report
28 min listen
Shifting Venture Investment Raises Concerns: A first of its kind study of venture investment in therapeutics by disease area and innovation finds that venture investment following the Great Recession has not yet recovered to the levels seen in the years leading up to the financial crisis. In ad... by The Bio Report
17 min listen
The Year in Biotech So Far and What’s Ahead: The biotech sector surged in the first half of the year despite volatile markets. M&A and financing continued to be robust as EvaluatePharma weighed in with its Pharma & Biotech Half-Year Report. We spoke to Jonathan Gardner, deputy news editor of EP... by The Bio Report
22 min listen
Enlisting Monoclonal Antibodies to Combat Bacterial Resistance: There’s growing global concern about threat from antibiotic resistant pathogens. That’s leading to new interest in looking beyond traditional antibiotics to monoclonal antibodies to address the problem. We spoke to Ken Stover, senior director of infe... by The Bio Report
21 min listen
The Lean Startup Takes Hold in the Life Sciences: The National Science Foundation and the National Institutes of Health, concerned about seeing the science they fund commercialized, have embraced the Lean Startup method as a way to improve the odds of success for new companies. Steve Blank, whose wo... by The Bio Report
23 min listen
Will Increased FDA Regulation of Diagnostics Speed or Slow Development of Personalized Medicine: The U.S. Food and Drug Administration is moving to expand its regulatory domain by adding oversight of certain diagnostics it does not regulate today. The agency says thousands of these test are used daily to guide treatment decisions and diagnose di... by The Bio Report
27 min listen
What to Do About the United States’ Declining Investment in R&D: Investment in biomedical research in the United States is declining at a time when other countries have been increasing their spending. While this is raising concerns about the threats this poses to the nation’s economic competitiveness, a new study ... by The Bio Report
16 min listen
How One Company Is Reinventing Drug Development: Tomasz Sablinski believes the drug development process is broken and has sought to reinvent it. His company, Transparency Life Sciences, relies on crowdsourcing to design its clinical trials, makes all of its data public, and employs digital technolo... by The Bio Report
34 min listen
What Activist Investors Can Teach Biotech Companies: To improve the long-term value of biopharmaceutical companies, management should learn to think more like activist investors, according to a new report from EY. The report argues that capital allocation and strategic decision-making could benefit fro... by The Bio Report
16 min listen
A Look at the Year That Was in Biotech: The year 2014 was one for the record books for the biotech industry. In part one of a two-part podcast, we take a look back at the year that was with Adam Feuerstein, senior columnist for TheStreet.com. Feuerstein discusses the growing controversy ov... by The Bio Report
15 min listen
Why Interoperability Is Much More than a Technology Problem: A new government report finds that healthcare providers in the United States are increasing their adoption of health information technology, but their willingness to do so is tied to the incentives available. What’s more, the government is implementi... by The Bio Report
26 min listen
Calculating the Cost of Drug Development and What it Means: The cost of drug development, a metric that underlies discussions ranging from investment in startups to drug pricing, is a matter of great interest and controversy within the pharmaceutical industry. The Tufts Center for the Study of Drug Developmen... by The Bio Report
20 min listen
Reengineering Drug Discovery and Development: Drugmakers have employed new technologies to reduce the cost and time and it takes develop drugs and produce therapies that more precisely target the underlying biology driving diseases. Boston-based Berg Pharma is using artificial intelligence with ... by The Bio Report
21 min listen
Why Patent Trolling Threatens Biopharma: The biopharmaceutical industry has long been considered immune to the threat of patent trolls, patent holders who seek to monetize the value of a patent through enforcement rather than productive use. But a paper by UC Hastings Robin Feldman and Harv... by The Bio Report
16 min listen
Free Speech Ruling May Force FDA to Rethink Off-Label Marketing: Earlier this month in a preemptive challenge from Amarin Pharma against the U.S. Food and Drug Administration a federal judge ruled that the FDA cannot prohibit a drugmaker from promoting the off-label use of a drug if it does so through the dissemin... by The Bio Report
20 min listen
Reinventing Tech Transfer: Universities are moving away from a passive approach to technology transfer to engage with industry in new partnerships, put a greater emphasis on translational research, and nurturing technologies so they can give rise to new products and companies.... by The Bio Report
21 min listen
Examining The White House’s Plan to Combat Drug-Resistant Bacteria: Drug resistant bacteria cause 2 million illnesses and approximately 23,000 deaths each year in the United States, according to the U.S. Centers for Disease Control and Prevention. The problem of resistance also limits the ability to treat patients us... by The Bio Report
20 min listen
Why Privacy Concerns May Limit Big Data’s Payoff: Two-thirds of Americans say they are willing to anonymously share their health information with researchers, but only about 1 in 5 is willing to provide their purchase history or social media activity, according to a recent Truven Health Analytics-NP... by The Bio Report
14 min listen
TheStreet’s Adam Feuerstein Previews ASCO 2015: Wall Street’s attention will turn to Chicago as the annual meeting of the American Society of Clinical Oncology runs from May 29 to June 2. Some 5,000 abstracts became available mid-month and investors have been sifting through them to gain insights ... by The Bio Report
14 min listen
Home-Brew Morphine, Dual Use Technology, and the Biologist’s Repsonsibilities: A recent article in Nature Chemical Biology that shows it is possible to convert sugar into morphine with genetically engineered yeast has sparked public attention over the potential illicit use of the technology and the need for regulation. The work... by The Bio Report
20 min listen

More Episodes from The Bio Report

Skip carousel

Teaching an Old Drug a New Trick to Prevent Lyme Disease: Each year, an estimated 400,000 people in the United States will be diagnosed with Lyme disease, a billion-dollar healthcare problem caused by a bacterial infection that is transmitted through the bite of a tick. The condition can cause joint pain an... by The Bio Report
20 min listen
A New Class of Cell Therapies to Target Solid Tumors: In February, the U.S. Food and Drug Administration approved the first tumor-infiltrating lymphocyte, or TIL therapy, for solid tumors. The approval was hailed as a milestone that points the path forward for a new class of cell therapies for solid tum... by The Bio Report
33 min listen
Targeting the Tumor Microenvironment with Lipid-Based Immunotherapies: Lipids have long been used as drug delivery vehicles, but HighField Biopharmaceutics is repurposing lipids as drugs to fight cancer. The company’s technology platform is seeking to change the immunotherapy landscape with new treatments that are bette... by The Bio Report
35 min listen
A Company Born from a Father Who Wore His Heart on His Sleeve: Jeremiah Robison’s daughter Sofia was born with cerebral palsy, a congenital movement disorder. Watching her physicians use body monitors to measure her gait, and later apply functional electrical stimulation as physical therapy, gave him an idea to ... by The Bio Report
32 min listen
Using AI to Improve Burn Care: Physicians treating people with burns typically incorrectly assess the depth of burn wounds in about 25 to 30 percent of cases. That, in part, is due to a lack of diagnostic tools to assess the severity of a burn and to determine the best approach to... by The Bio Report
24 min listen
A Home for Biotech in the City that Never Sleeps: New York City is not the first place that comes to mind when thinking of biotech clusters, but the Big Apple has been a growing center of biomedical innovation with its mix of academic research hospitals, finance, and growing number of biopharmaceuti... by The Bio Report
33 min listen
Biopharma R&D Growing Stronger: Funding levels, drug launches, and R&D success rates all grew in 2023, according to a new report from the IQVIA Institute for Human Data Science. Global funding of biopharmaceutical research and development increased to $72 billion, up from $61 b... by The Bio Report
31 min listen
The Benefits of Having a Multitude of Cins: In January 2023, AstraZeneca agreed to acquire CinCor Pharma, the CinRx cardio-renal disease therapy subsidiary, for $1.3 billion. The deal included a potential additional $500 million milestone payment. The price represented a 121 percent premium to... by The Bio Report
33 min listen
Making ADCs Smarter and Safer with a Simple Twist of Fate: Antibody-drug conjugates can deliver chemotherapy directly to tumors but more than 95 percent of the dose often ends up in healthy tissues, decreasing efficacy and increasing toxicity. Mythic Therapeutics FateControl technology improves the uptake of... by The Bio Report
24 min listen
Targeting a Natural Repair System to Restore Brain Health: The HGF/MET neurotrophic system plays a critical role in the maintenance and repair of connections in the brain. Enhanced signaling along this pathway has the potential to reduce inflammation, slow neurodegeneration, and provide neuroprotection. Athi... by The Bio Report
19 min listen
Programing Cells in a Predictable and Scalable Way: The advent of induced pluripotent stem cells, cells that can be coaxed into becoming virtually any type of cell within the body, promised to usher in a new era of regenerative medicine and improved drug discovery. In practice, though, the ability to ... by The Bio Report
32 min listen
Why DNA May Be the Data Storage Medium of the Future: Some 100 trillion gigabytes of data are created and consumed each year, an amount that is expected to double by 2025. The demand for data storage carries the need for significant physical space and power requirements in the form of digital data cente... by The Bio Report
32 min listen
Scouring Genetic Variation within Our Cells for Drug Targets: People tend to think of each person having their own unique genome. Quotient Therapeutics is taking an approach to drug discovery based on the reality that from cell to cell within a given individual, there can be trillions of divergent genomes. Chan... by The Bio Report
26 min listen
Correcting Gene Dysregulation to Treat Diseases: Regardless of the cause of a disease, most diseases involve gene dysregulation. Omega Therapeutics is developing a new class of programmable, epigenomic, mRNA medicines designed to make specific epigenetic changes and correct abnormal gene expression... by The Bio Report
45 min listen
Using Technology to Regain Abilities after Spinal Cord Injury: The effects of spinal cord injury extend beyond the loss of mobility. They can include a toll on mental health, a feeling of exclusion, and a general decline in the quality of life as a result of being able to stand and interact eye-to-eye with other... by The Bio Report
25 min listen
Why Drug Developers Have a Growing Interest in Targeting Mitochondria: Mitochondria are often referred to as the “powerhouses” of the cell, but as scientists gain a greater understanding of these essential organelles, they are coming to discover they play a more expansive role in health and disease. The Foundation for t... by The Bio Report
39 min listen
Beefing Up Computational Muscle to Understand Molecular Activity of Drug Candidates: Sandbox AQ, the Alphabet spin-out backed with $500 million in investment, in June 2023 unveiled it AQBioSim division. The division is working to bring SandoxAQ’s AI and quantum-inspired computing to develop new treatments for intractable medical cond... by The Bio Report
32 min listen
Targeting a Multitude of CIN in Cancer Cells: It’s long been understood that chromosomal instability (CIN) is a characteristic of cancer cells, but it also represents a key difference between cancer cells and healthy cells that can be exploited. Volastra is developing medicines for a wide range ... by The Bio Report
21 min listen
The Year in Biotech and What’s Ahead in 2024: Though the year began with a banking crisis and has been marked with layoffs and restructurings, we have managed to avoid a feared recession. It’s been a big year for new drug approvals, M&A activity has been brisk, and biotech stocks have rallie... by The Bio Report
33 min listen
Transforming Healthcare with Data: Vik Bajaj has long lived at the intersection of physical sciences, engineering, data science, and the life sciences—first as an academic working to improve diagnostic imaging at Stanford University and later as a chief scientific officer at GRAIL and... by The Bio Report
51 min listen
Realizing the Promise of IL-2 Therapies with AI: Interleukin-2 therapies have been seen as promising ways to treat solid tumors, but they have proven challenging because of the ability of IL-2 to both activate and suppress the immune system. Their effectiveness has been limited because of potential... by The Bio Report
23 min listen
Unlocking Real-World Data to Improve Outcomes: Real-world data promises to provide insights that lead to better therapies, change how we treat diseases, and improve outcomes for patients. One of the limits of realizing benefits from all of the health information we are swimming in is the lack of ... by The Bio Report
40 min listen
A Silicon Valley Entrepreneur Investing at the Intersection of Tech and Biotech: Artificial intelligence promises to reshape the healthcare landscape and deliver new insights into the molecular drivers of health and wellness, provide rapid diagnoses of patients, and discover and design therapies that extend beyond human imaginati... by The Bio Report
25 min listen
A Company Betting Its Physics-Based AI Will Fuel a Quantum Leap in Drug Discovery: Though many drug developers are harnessing AI to create novel chemical compounds, Iambic Therapeutic’s generative AI is leveraging quantum mechanics to get to better drugs. It says its physics-informed machine learning approach has yielded promising ... by The Bio Report
24 min listen
Detecting Alzheimer’s Disease Early through a Blood Test: One of the challenges with treating Alzheimer’s disease is diagnosing patients early enough in the course of its progression to have a meaningful impact with treatments. Sunbird Bio said it can accurately detect and differentiate specific proteins th... by The Bio Report
25 min listen
Addressing Supply-Chain Challenges Underlying Drug Shortages with Synthetic Biology: About 40 percent of all drugs in the Western world are derived from plants. But challenges with producing a reliable supply inherent with materials derived from agricultural processes can lead to drug shortages as climate events, pests, and plant dis... by The Bio Report
28 min listen
Building Better and More Affordable Vaccines: The COVID 19 pandemic provided a painful reminder of the global need to protect people against the threat of existing and emerging infectious diseases. Emergex Vaccines is developing fully synthetic vaccines that provide advantages over live attenuat... by The Bio Report
42 min listen
Overcoming Resistance to Targeted Therapies: The advent of targeted therapies has contributed to notable progress in the fight against cancer, but the ability of cancers to develop resistance to these precision medicines continues to leave patients in need of new approaches. Concarlo Therapeuti... by The Bio Report
30 min listen
Using Tumor Gene Therapy to Overcome Barriers to Immunotherapies: There have been significant advances to immunotherapies since their first introduction, but challenges remain to realizing their full potential in solid tumors. That’s because of the ability of tumors to use multiple mechanisms to evade the immune sy... by The Bio Report
30 min listen
Using AI to Generate Mini-Protein Therapeutics: Mini-proteins have the power and performance of an antibody with the ability to bind tightly to a target. But because of their small size, it can penetrate into places where small molecules can go. Ordaōs Bio is leveraging its generative AI platform ... by The Bio Report
28 min listen

Related podcast episodes

Skip carousel

Hume and the Politics of Enlightenment by Free Thoughts
50 min listen
Rupert Murdoch: The Succession Prequel: How a young man turned a failing Australian newspaper into a global media empire. by Good Bad Billionaire
52 min listen
Rainer Zitelmann & Chris Burgard on The Pelle Neroth Taylor Show - 04 March 2024: GUEST 1 OVERVIEW: Rainer Zitelmann is a historian, sociologist and multiple bestselling author, whose books include Hitler’s National Socialism, The Power of Capitalism and In Defense of Capitalism. He published 28 books. His books have been transla... by TNT Radio
55 min listen
Andrew Revkin - The Death of Science Writing, and the Future of Catastrophe: We live in a science centered age—a time of private spaceflight and personalized medicine, amid path-breaking advances in biotechnology and nanotechnology. And we face science centered risks: climate and energy crises, biological and nuclear... by Point of Inquiry
33 min listen
Episode 62: J.J. Kimche "Is the Zohar Authentic?" by JUDAISM DEMYSTIFIED | A Guide for Today's Perplexed: Confronting the Challenges of This Generation
136 min listen
Journeys in Earth's Extinct Ecosystems: Thomas Halliday on paleobiology, croquet and the inevitable end of our species by Keen On
34 min listen
Seg. 1: COVID-19 Myths & Facts | Seg. 2: Truman's Crisis Leadership | Seg. 3: Pandemic Gardening: Segment 1: What we know about COVID-19, and what we don't A lot is unknown about the novel coronavirus currently circulating the globe, giving rise to myths about how it spreads, how to keep it from spreading and how to reduce one's chances of getting by Central Standard
57 min listen
#20 - Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology: In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. Part I serves as an introduction to Tom, his by The Peter Attia Drive
74 min listen
Deborah Blum - Murder and Chemistry in Jazz Age New York: For many of us, chemistry is something we remember with groans from high school. Periodic Table of the Elements—what a pain to memorize, and what was the point, anyway? So how do you take a subject like chemistry and make it exciting, ... by Point of Inquiry
35 min listen
Steven Lukes on Émile Durkheim: If anyone can lay claim to be the father of sociology, it’s Émile Durkheim. By the time of the French academic’s death in 1917, he’d produced an extraordinary body of work on an eclectic range of topics, and had become a major... by Social Science Bites
18 min listen
A Look Back: Jeffrey Epstein As Told By Michael Wolff: Michael Wolff is an American author, journalist, and columnist known for his work in the field of media and politics. He was born on August 27, 1953, in Paterson, New Jersey. Wolff has had a varied career, working in print, television, and digital... by The Epstein Chronicles
11 min listen
The Smartest Guy In The Room, Tom Woods: The Smartest Guy In The Room, Tom Woods Thomas E. Woods, Jr., is the 2019 winner of the Hayek Lifetime Achievement Award from the Austrian Economics Center in Vienna. He is a senior fellow of the and host of , which releases a new... by Outer Limits Of Inner Truth
32 min listen
Lockdown Planet: How has one year of lockdown changed our environment in the UK and around the world? by Costing the Earth
28 min listen
Episode 492: Who Was the Marxist Robert Kurz? (ft. Nick Gruber): Robert Kurz was a German Marxist philosopher, social critic, journalist and editor of the journal... by Diet Soap - a podcast
58 min listen
Is America Permanently Broken? with Naomi Wolf by Tom Mullen Talks Freedom
30 min listen
Richard Rhodes — Energy: A Human History: This is one of the best dialogues Dr. Shermer has ever had in his quarter century of talking to the leading scientists and scholars of our time. Listen in as he and Pulitzer Prize- and National Book Award-winning author Richard Rhodes discuss nuclear... by The Michael Shermer Show
80 min listen
Hadith: Ernie Rea and guests discuss the Hadith, the stories and traditions of Muhammad's life. by Beyond Belief
28 min listen
MWV Episode 41 - Inside the Mind's Eye: Communicating Science in a New Media Era (mp3): Blogs, podcasts, and other new media outlets have changed the way people get their news. Immediate access to information presents new opportunities as well as challenges for science communication. Watch Carl Zimmer, science writer for the New York... by MicrobeWorld Video
73 min listen
Moby Dick by Writ Large
26 min listen
Cuban Cure - Moral Panics: Laurie explores Cuba's success in developing world-beating bioscience. Also moral panics. by Thinking Allowed
28 min listen
Robert Thurman on Enlightenment, Time, Skepticism, and Science [rebroadcast] by A Skeptic's Path to Enlightenment
66 min listen
Sir Thomas More: Who was Thomas More - Knight, Chancellor and Martyr - regarded as both saint and persecutor, Humanist intellectual and bigoted zealot? His religious writings, with their, at times, violent attacks on what he regarded as heresy, have been hotly debated. by Not Just the Tudors
40 min listen
Brendan Simms, "Hitler: A Global Biography" (Basic Books, 2019): Simms argues that fears that Germany would lose the economic and demographic competition with Britain and especially the US sat at the heart of Hitler's world view... by New Books in Genocide Studies
29 min listen
Who Is Fox News?: Sean Morrow explores the backstory of Fox News and its founders: media savant Roger Ailes and Australian billionaire Rupert Murdoch by Who Is?
51 min listen
MWV Episode 39 - Carl Zimmer: Newspapers, Blogs, and Other Vectors: Infecting Minds with Science in the Age of New Media (30 min.): MicrobeWorld Video (Apple TV|HD) by MicrobeWorld Video
31 min listen
Conspiracy Culture in American History by Lectures in History
88 min listen
Special Episode: Todd May, Philosopher and Consultant on The Good Place!: Our second “insider” conversation with someone who worked on The Good Place! Todd May is a philosopher to whom Michael Schur reached out early in the show because of Professor May’s book Death (The Art of Living). Todd talks and laughs with Jon Spira... by Tov! A Podcast About ”The Good Place” and Jewish Ideas
57 min listen
From Cautionary Tales: The Mummy's Curse by Digital Folklore
44 min listen
Jeremy Beck & Taylor Hudak on The Dean Mackin Show - 25 January 2024: GUEST HOST: David McBride filling in for Dean Mackin. On today's show, Jeremy Beck discusses breaking global news. Taylor Hudak discusses the fight against tyranny and breaking developments in support of Julian Assange. GUEST 1 OVERVIEW: Jeremy Beck ... by TNT Radio
56 min listen
Walter Williams on Life, Liberty and Economics: Radio Host, Columnist, and Professor Walter Williams talks about his early days as an economist, the Civil War, markets, and some deep but simple economic principles. by EconTalk
63 min listen

Discover this podcast and so much more

Chronicling a Trailblazer of the Genomics Age

Chronicling a Trailblazer of the Genomics Age

Description

Titles in the series (100)

More Episodes from The Bio Report

Related podcast episodes