Health research involving people in marginalized populations can be challenging, and recruitment is often difficult. One approach, respondent-driven sampling, takes advantage of connections between people in these groups, who recruit each other in a chain-referral (friend of a friend) manner. In this interview, Dr. Ann Jolly, Associate Professor in the School of Epidemiology, Public Health and Preventive Medicine at the University of Ottawa, discusses the importance of reaching these marginalized populations. Dr. Jolly and colleagues published an analysis article in CMAJ. Full article: https://www.cmaj.ca/lookup/doi/10.1503/cmaj.141076To request a transcript of this podcast, contact cmajgroup@cmaj.ca