There are a record number of cholera outbreaks around the world today.   Consider this data point. In 2022 alone, 29 countries have reported a cholera outbreak. This compares to 20 countries over the previous five years. The outbreaks are distributed across several regions: countries in the Caribbean, middle east, Africa, and Asia are experiencing cholera outbreaks -- some for the first time in decades. Amidst all these concurrent outbreaks, there is a global shortage of cholera vaccines to the point that public health officials are suspending the the standard two-dose vaccination regimen in favor of just a single dose.  In this episode, we speak with Louise Ivers, director of the Harvard global health institute, and the Massachusetts general hospital center for global health about why there a sudden surge in outbreaks worldwide, where are the outbreaks the worst, and what can be done about this vaccine shortage.