Global markets are wavering as cases of the omicron variant ticks up around the world. Moderna says its Covid booster dose does bolster antibodies against the new variant, but even so, CNBC’s Robert Frank reports that big banks are reversing their return-to-work policies. CNBC’s Meg Tirrell explains the Moderna news and compares data on cases of Covid’s omicron and delta variants, and former FDA Commissioner Dr. Scott Gottlieb offers best testing practices to families hoping to gather for a safe holiday. In light of the latest surge, the World Economic Forum usually held in January in Davos has been postponed. Plus, CNBC’s Eamon Javers discusses Senator Joe Manchin’s (D-WV) decision not to support President Biden’s Build Back Better plan, a blow for Democrats and the administration.  In this episode:Dr. Scott Gottlieb, @ScottGottliebMDRobert Frank, @robtfrankMeg Tirrell, @megtirrellJoe Kernen, @JoeSquawkBecky Quick, @BeckyQuickAndrew Ross Sorkin, @andrewrsorkinKatie Kramer, @Kramer_Katie