AstraZeneca has unveiled new data on its Covid-19 vaccine, revealing that it’s 79% effective at preventing symptomatic cases. CNBC’s Meg Tirrell explains the news, and AstraZeneca U.S. SVP and President of the Biopharmaceuticals Business Unit Dr. Ruud Dobber shares details and implications from the new study. Some of Wall Street’s junior bankers are banding together to shine a light on the 100 hour work weeks taking a toll on their physical and mental health. New York Times reporter Kate Kelly and Vanity Fair special correspondent William Cohan discuss the generational divide on Wall Street, from work ethic to work-life balance. The wealthiest Americans are finding ways to avoid their taxes, ARK’s Cathie Wood has a new price target for Tesla, and the Kernens are betting on their (individual) basket brackets. Plus, happy 90th birthday William Shatner!