On this week’s episode of Fast Facts - Perio Edition, Katrina Sanders, talks to us about another condition that aligns with the classification system, Periodontitis as a Manifestation of Systemic Disease, Hypophosphatasia.    Quotes:    “Individuals who experience Hypophosphatasia are oftentimes individuals who experience impaired mineralization or an impaired calcification, particularly of the bones and the teeth.”   “From an oral component, the most frequent dental signs that we do see is seen in premature loss of primary teeth.”   “There is treatment readily available. There is a medication that is oftentimes delivered via injection. However, one of the challenges associated with utilizing this type of an injection is that you can oftentimes see increase in calcium or calcium deposits as noted in the corners of the eyes on your patients.”   Resources:   DentistRX: https://www.dentistrx.com  More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/    Katrina Sanders Website: https://www.katrinasanders.com  Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/    Plagmann HC, Kocher T, Kuhrau N, Caliebe A. Periodontal manifestation of hypophosphatasia. A family case report. J Clin Periodontol. 1994 Nov;21(10):710-6. doi: 10.1111/j.1600-051x.1994.tb00791.x. PMID: 7852617.