Eric Topol and Abraham Verghese reflect on 2021's extraordinary podcast guests, and how we excelled in science and healthcare but were tripped up by the vagaries of human behavior. This podcast is intended for US healthcare professionals only. For more episodes of Medicine and the Machine https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Editor-in-Chief, Medscape Abraham Verghese, MD, Physician, author, and educator; Professor and Vice Chair, Theory & Practice of Medicine, Department of Medicine, Stanford University, Stanford, California You may also like: Medscape's Chief Cardiology Correspondent, Dr. John M. Mandrola's, This Week In Cardiology https://www.medscape.com/twic Discussions on topics at the core of cardiology and the practice of medicine with Dr. Robert A. Harrington and guests on the Bob Harrington Show https://www.medscape.com/author/bob-harrington For questions or feedback, please email: news@medscape.net