​​The Arizona Cardinals present a lot of change around QB Kyler Murray. He welcomes college teammate Marquise Brown but must wait out a PED suspension for DeAndre Hopkins. Can Cooper Kupp and the Los Angeles Rams repeat their magic from last year? Is Cam Akers or Darrell Henderson the backfield target? We fully expect the San Francisco 49ers to move on to Trey Lance. What does that mean for the fantasy football draft values of Deebo Samuel, Brandon Aiyuk and George Kittle? And we know the Seattle Seahawks want to run the ball. A lot. We don't know, however, who will run more between Kenneth Walker and Rashaad Penny ​or​ who will throw passes to D.K. Metcalf and Tyler Lockett. Let's sort through it all to kick off this 8-part fantasy football podcast series ...Arizona Cardinals ... 1:59Los Angeles Rams ... 27:30San Francisco 49ers ... 49:31Seattle Seahawks ... 1:12:47Check out our full 2022 fantasy football rankings. Build your own custom draft board here.