In this high yield episode, we review the clinical presentation, up front investigations, immediate and long-term management of patients who present with STEMIs - one of the 5 causes of life-threatening chest pain. Our medicine minute reviews the PLATO trial, which supports the use of ticagrelor over clopidogrel as the second agent in dual anti-platelet therapy in patients with ACS. Written by: Drs. Varun Srivatsav and William Kennedy (Internal Medicine Residents)Reviewed by: Dr. Jonathan Dean (GIM) and Dr. Andrea Lavoie (Cardiology)Sound Editing by: Nathan Doupnik (Medical Student)Infographic by: Drs. Varun Srivatsav and William Kennedy (Internal Medicine Residents)Infographic edited by: Vincent Li (Medical Student)This episode was supported by Spatula Foods. Enjoy elevated cuisine every day with high-quality dishes you can cook yourself in just 10 minutes. Go to https://www.spatulafoods.com and use promo code INTERN for $40 off your first box- this will help support our podcast! Support the show