So in our Toxidrome Roadside to Resus episode we covered the initial management of a poisoned patient, some of the constellation of features to look out for and the specific management. But what about specific agents and circumstances that require particular knowledge and management both in the prehospital environment and in ED? Well in this episode we’ll cover these by running through; Paracetamol poisoning and treatment Calcium channel blocker overdose Beta blocker overdose High dose insulin euglycaemic therapy Activated charcoal Intralipid therapy Cardiac arrest due to toxicology We'd love to hear any comments or feedback you have and make sure to take a look at the references and resources below. Enjoy! Simon, Rob & James