The deployment of rules to the security stack across all data islands, cloud, SaaS applications, data centers, and mobile devices designed to manifest an organization's cybersecurity first principle strategies of zero trust, intrusion kill chain prevention, resilience, and risk forecasting. 
CyberWire Glossary link: https://thecyberwire.com/glossary/policy-orchestration
Audio reference link: “The Value of Using Security Policy Orchestration and Automation,” by David Monahan, uploaded by EMAResearch, 3 April, 2018