26 min listen
The Genetic Testing (R)Evolution
FromRaising Health
ratings:
Length:
32 minutes
Released:
Jun 15, 2021
Format:
Podcast episode
Description
Genetic testing is on the cusp of a major revolution, which has the potential to shift not just how we understand our risk for disease, but how we practice healthcare. In the clinic today, genetic testing is used only in cases where we know that mutations have big impact on physiology (BRCA mutations in breast cancer, for example). But our knowledge of how our genetics influences our risk for disease has evolved, and we now know that many (tens of thousands to even millions) small changes in our genes, each of which individually has a tiny effect, combine to influence our risk profile. This new appreciation — coupled with powerful statistical methods and massive datasets — has fueled the creation of a new tool to quantify the risk of a broad range of common diseases: the polygenic risk score. On this episode, which originally aired on January 18, 2021, host Lauren Richardson (@lr_bio) is joined by Peter Donnelly, (@genemodeller Professor of Statistical Science at the University of Oxford and the CEO of Genomics PLC,) and Vineeta Agarwala, (@vintweeta physician-scientist and general partner at a16z), to discuss these scores and how they can reshape healthcare, away from a paradigm of treating illness and towards prevention and maintenance of health.
Released:
Jun 15, 2021
Format:
Podcast episode
Titles in the series (100)
Going Back to the Workplace in a Pandemic: It's not normal to talk to your employer about the details of your health: your current temperature, who you've been exposed to, whether your kid is sick, whether or not you've been social distancing. So how do employers handle and manage this entirely new process of employees returning to the workplace in the midst of an ongoing pandemic? In this episode of Bio Eats World, Vineeta Agarwala (general partner at a16z), Phong Nguyen (EVP and General Manager at Accolade), Ryan Sandler (CEO and Cofounder of Truework), and Mark Sendak (Population Health & Data Science Lead at the Duke Institute for Health Innovation) talk about what it means for employers to now have to manage employee health in a whole new way, figuring out when it's safe to come back, how, and what tools you need. From monitoring employee health and preventing transmission to triaging what happens when there is a documented case; temperature checks (do they even make sense?); te by Raising Health