Severe mental illness (SMI) refers to mental disorders that result in significant functional impairment (e.g., schizophrenia and bipolar disorder).  In this episode, we bring you Part 1 of our conversation with Lisa Eyler, Ph.D., about inflammation in individuals with SMI, how inflammation is associated with accelerated aging and other health problems, and the clinical utility of functional magnetic resonance imaging (fMRI) in this population.  We also contrast the approaches of the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) and the Research Domain Criteria (RDoC). Show notes are available at www.NavNeuro.com/31 _________________ If you’d like to support the show, here are a few easy ways: 1) Tell your friends and colleagues about it 2) Subscribe (free) and leave an Apple Podcasts rating/review: www.NavNeuro.com/itunes  3) Contribute to the discussion in the comments section of the website (click the episode link listed above) or on Twitter (@NavNeuro)   Thanks for listening, and join us next time as we continue to navigate the brain and behavior!   [Note: This podcast and all linked content is intended for general educational purposes only and does not constitute the practice of psychology or any other professional healthcare advice and services. No professional relationship is formed between hosts and listeners. All content is to be used at listeners’ own risk.  Users should always seek appropriate medical and psychological care from their licensed healthcare provider.]