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144 - mRNA Technologies and their Implications in Therapeutics: Q&A with Dr. Martin

144 - mRNA Technologies and their Implications in Therapeutics: Q&A with Dr. Martin

FromHelixTalk - Rosalind Franklin University's College of Pharmacy Podcast


144 - mRNA Technologies and their Implications in Therapeutics: Q&A with Dr. Martin

FromHelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

ratings:
Length:
28 minutes
Released:
Mar 1, 2022
Format:
Podcast episode

Description

In this episode, we interview Dr. Danyelle Martin, a Medical Science Liaison (MSL) at Moderna, in order to learn more about the what, how, and future of mRNA-based therapeutics, and what impact it can have on healthcare and healthcare professionals in general. Key Concepts Moderna has a “Research Engine” proprietary service that takes an mRNA idea from a web-based digital designer, to a digital ordering system, and finally to a production facility where mRNA constructs are synthesized and quality tested. Pharmaceutics play a big role in the formulation of mRNA particles. Lipid nanoparticles (LNPs) play an important role for stability and delivery of mRNA cargo. After LNPs and mRNA are co-formulated, the product is purified, filtered, frozen, and subjected to a series of good manufacturing practice (GMP) tests to ensure product quality. COVID-19 vaccines are a small glimpse into the potential future of mRNA-based therapeutics. Moderna’s pipeline includes mRNA vaccines for other viruses (including RSV, influenza, Zika and CMV) as well as therapeutics for non-viral diseases (including a personalized cancer vaccine and a VEGF-A mRNA molecule for myocardial ischemia).
Released:
Mar 1, 2022
Format:
Podcast episode

Titles in the series (100)

Educational podcast presented by the Rosalind Franklin University College of Pharmacy. This podcast is produced by our pharmacy faculty to supplement study material and provide relevant drug and professional topics. We're hoping that our real-life clinical pearls and discussions will help you stay up-to-date and improve your pharmacy knowledge.