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Circular RNAs as Urinary Biomarkers

Circular RNAs as Urinary Biomarkers

FromClinical Chemistry Podcast


Circular RNAs as Urinary Biomarkers

FromClinical Chemistry Podcast

ratings:
Length:
13 minutes
Released:
Nov 6, 2019
Format:
Podcast episode

Description

Circular RNAs have the unique topological feature of circularity among the RNAs species.  They are single-stranded, covalently closed, circular RNA molecules and are hypothesized to be generated largely through back-splicing of exons from precursor messenger RNAs.  Circular RNAs were once considered as aberrant splicing by-products, which were only present in minute amounts in cells.  The potential of this RNAs species as a disease biomarker is to be explored, but there are biological properties of circular RNAs which make them suitable for biomarker development. An Editorial appearing in the October 2019 issue of Clinical Chemistry by Drs. Jacky Lam and Dennis Lo discussed circular RNAs as potential urinary biomarkers. 
Released:
Nov 6, 2019
Format:
Podcast episode

Titles in the series (100)

This free monthly podcast is offered by Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory. In addition to being the most cited journal in the field, Clinical Chemistry has the highest Impact Factor (7.292 in 2019) among journals of clinical chemistry, clinical (or anatomic) pathology, analytical chemistry, and the subspecialties, such as transfusion medicine and clinical microbiology.