Join ED clinical pharmacist Jimmy Pruitt and Dan McCollum as we discuss the reasons that the traditional "B52" cocktail of haloperidol, lorazepam, and diphenhydramine is badly in need of updating. Why this cocktail is slower than you think. Newer medications that are more effective. Smarter approaches to agitated patients. When ketamine should be used. This podcast is being cross published with the "Pharm So Hard" podcast, an excellent podcast discussing many excellent clinical pharmacology topics.