Answer all your burning questions (and your patients’ burning questions) about the different COVID-19 vaccines currently authorized in the US. Infectious diseases / HIV expert, Dr Monica Gandhi (https://en.wikipedia.org/wiki/Monica_Gandhi) @MonicaGandhi9 (https://twitter.com/monicagandhi9?lang=en) (UCSF) joins us to cover: the Pfizer-BioNTech and Moderna novel mRNA vaccine mechanisms, trial data, and practicalities of who should receive them.  We discuss data around the Oxford-AstraZeneca adenovirus vaccine, which is authorized in the UK and India, and may be available in the US later this year.  Feel confident recommending COVID-19 vaccines to your patients!

Episodes (https://thecurbsiders.com/episode-list) | Subscribe (http://thecurbsiders.libsyn.com/feed) | Spotify (https://open.spotify.com/show/3SKlzOLxyztvA1BkJfnf67) | Swag! (https://www.teepublic.com/user/kashlakmemorial) | Top Picks (https://thecurbsiders.com/top-picks) | Mailing List (https://thecurbsiders.com/knowledgefood) | thecurbsiders@gmail.com (mailto:thecurbsiders@gmail.com) | Free CME! (http://curbsiders.vcuhealth.org)

Credits

Written and Produced by: Molly Heublein, MD

Cover Art: Chris Chiu, MD, FACP, FAAP

Infographic: Tima Karginov

Hosts: Chris Chiu, MD, FACP, FAAP; Molly Heublein, MD; Paul Williams, MD, FACP

Editor: Emi Okamoto MD (written materials); Clair Morgan of Nodderly.com (https://www.nodderly.com/) (audio)

Guest: Monica Gandhi, MD, MPH

Sponsor: Panacea Financial 
This episode is supported by Panacea Financial, digital banking built for doctors, by doctors. At Panacea Financial you can have your own free personal banker and a support team that works around the clock- just like you do. Open your free checking account today athttp://panaceafinancial.com

Panacea Financial, a Division of Sonabank, Member FDIC

Sponsor: VCU Health CE
The Curbsiders are partnering with VCU Health Continuing Education (https://cme.vcuhealth.org/) to offer FREE continuing education credits for physicians and other healthcare professionals. Visit http://curbsiders.vcuhealth.org.

Time Stamps

Intro, disclaimer, guest bio - 00:00

 Guest one-liner, book recommendation - 3:40

Authorized vaccines in the US - 8:30

AstraZeneca vaccine mechanism- 9:26

mRNA vaccine mechanism - 10:30

Vaccine distribution issues (cold chain) - 16:05

mRNA safety - 18:24

mRNA vaccine efficacy/data from phase 3 trials - 19:40

How did we get this so quickly - 23:40

Vaccine impact on asymptomatic infection - 26:18

AstraZeneca trials - 28:20

Pregnancy - 35:10

Anaphylaxis - 37:10

Prior COVID-19 infection - 39:07

Side effects - 42:05

Pediatric patients - 45:12

Phases of role outs in the US -46:50

Herd immunity - 48:16

Thoughts of how to make this happen - 52:45

Preexisting conditions - 53:40

How long will immunity last - 57:15

Mutant strains - 58:25

Future of mRNA vaccines - 1:00:30

Take home points and Outro - 1:02:12