In this VETgirl online veterinary continuing education podcast, we review anticoagulant rodenticide (ACR) toxicity in cats. First off, let's have a quick refresher on ACRs in our small animal patients! Remember that ACRs interfere with the production of clotting factors II, VII, IX, and X by inhibiting an enzyme called vitamin K1 epoxide reductase (DeClementi). When these clotting factor levels drop low enough, the patient can develop clinical manifestations of disease (e.g., hemorrhage).