To safely re-open a business, you need more than masks. Covid testing is key – and the options are changing quickly. We found the most in-the-know person in public health to walk us through the choices, costs, and protocols to keep an entrepreneurial team, and all of us, safe. Rajiv Shah is president of the Rockefeller Foundation, which has led response to health crises in the United States and around the world for 100 years (including the 1918 flu pandemic). Applying what he learned fighting the Ebola outbreak in West Africa, Shah has brought together business, government, and health officials to turbo-charge Covid testing development. Next-gen test kits are coming soon: cheaper, easier, more abundant. If deployed correctly, says Shah, they can make us all safer and healthier in 2021.