ACR osteoarthritis guidelines author, Dr. Tuhina Neogi (Boston University; @tuhinaneogi) schools us on all things OA, including new understandings of pathophysiology, diagnosis, when to order imaging and labs, and an overview of pharmacologic and nonpharmacologic therapies. Plus, get answers to your questions from Twitter on CBD, turmeric, glucosamine, chondroitin, NSAIDS, intra-articular steroid and hyaluronic acid injections, tai chi, and more! ACP members can claim CME-MOC credit at https://www.acponline.org/curbsiders (CME goes live at 0900 ET on the episode’s release date).  Full show notes at https://thecurbsiders.com/episode-list. Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Credits Written (including CME questions) and Produced by: Beth Garbitelli and Matthew Watto MD, FACP Cover Art and Infographic by: Beth Garbitelli Hosts: Beth Garbitelli, Matthew Watto MD, FACP; Paul Williams MD, FACP Editor: Matthew Watto MD, FACP Guest: Tuhina Neogi MD, PhD Partners Win a prize! Celebrate National Internal Medicine Day and tell us why you’re I.M. Proud. Tell us why you are I.M. Proud and enter the contest by visiting www.acponline.org/improud to submit your story today! Answer one of the three questions below and share your story on social media using the hashtags #IMProud #NationalInternalMedicineDay, and tag @acpinternists. Prizes will be given out 3 times through June of 2020. The first group of winners will be announced on the first ever National Internal Medicine Day October 28, 2019! What makes you proud to practice internal medicine or one of the I.M. subspecialties?  What recent patient experience made you proud to be an internist or subspecialist? How is internal medicine unique from other subspecialties? See us at the CHEST 2019 Annual Meeting in New Orleans! We’ll be doing two live interviews on stage, plus recording two recap episodes to bring you high yield clinical pearls from the conference. Look out for us in our red Curbsiders shirts and say hello. Take a picture with Stuart! Give Paul a hug! Register today https://chestmeeting.chestnet.org/ !!!!   Time Stamps 00:00 Sponsor: ACP’s National Internal Medicine Day I.M. Proud Story Contest 00:15 Cold open, disclaimer, intro and guest bio 05:44 Guest one-liner, Picks of the Week*: Joe Nesbo mystery novels, The Snowman (film), Midsommar (film), Won’t You Be My Neighbor (film), @vermontkitchen Beth’s food blog, Serious Eats; Buy Yourself a Ballistic Jump Rope 07:55 Dr. Neogi’s Women in Medicine moment of awakening 15:40 Sponsor: ACP’s National Internal Medicine Day I.M. Proud Story Contest 17:35 Case of Osteoarthritis; Initial history and exam 23:23 Imaging for osteoarthritis 28:45 Physical exam for OA 31:45 Osteoarthritis risk factors 33:48 Pathophysiology of OA 37:43 Targeted therapies for OA are in the pipeline; Weight loss and joint protection 41:35 Mechanisms of pain in OA and recognizing pain phenotypes 46:58 Mainstays of osteoarthritis treatment 49:56 Capsaicin, Acetaminophen, and the importance of positivity 52:22 Intra-articular injections with corticosteroids or hyaluronic acid 57:25 Occupational therapy, More on Topical and Oral NSAIDS; SNRIs (duloxetine)   62:00 Questions from Twitter: CBD and marijuana (cannabis), turmeric, fish oil (omega 3 fatty acids) 65:03 More from Twitter: Glucosamine/chondroitin, acupuncture, tai chi, yoga, mindfulness, meditation 70:42 New targets for osteoarthritis; Take Home Points 73:40 Outro *The Curbsiders participates in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising commissions by linking to Amazon. Simply put, if you click on my Amazon.com links and buy something we earn a (very) small commission, yet you don’t pay any extra. Goal Listeners will learn to classify osteoarthritis (OA), assess symptom mana