The biggest female movie star of the last 30 years, "America's Sweetheart" herself, reflects on pre-stardom life and loss, how she wound up in 'Pretty Woman' and becoming the queen of rom-coms and what it's like to now be playing a mom (she's getting some of the best notices of her career for her turn as a mother trying to help her drug-addicted son in Peter Hedges' latest film) and starring on series TV.