Recently at the 30th anniversary conference of the Council for Secular Humanism in Los Angeles, leading science blogger PZ Myers and Point of Inquiry host Chris Mooney appeared together on a panel to discuss the questions, "How should secular humanists respond to science and religion? If we champion science, must we oppose faith? How best to approach flashpoints like evolution education?"
It's a subject about which they are known to... er, differ.
The moderator was Jennifer Michael Hecht, the author of Doubt: A History. The next day, the three reprised their public debate for a special episode of Point of Inquiry, with Hecht sitting in as a guest host in Mooney's stead. 
This is the unedited cut of their three way conversation.
PZ Myers is a biologist at the University of Minnesota-Morris who, in addition to his duties as a teacher of biology and especially of development and evolution, likes to spend his spare time poking at the follies of creationists, Christians, crystal-gazers, Muslims, right-wing politicians, apologists for religion, and anyone who doesn't appreciate how much the beauty of reality exceeds that of ignorant myth.
Jennifer Michael Hecht is the author of award-winning books of philosophy, history, and poetry, including: Doubt: A History (HarperCollins, 2003); The End of the Soul: Scientific Modernity, Atheism and Anthropology (Columbia University Press, 2003); and The Happiness Myth, (HarperCollins in 2007). Her work appears in The New York Times, The Washington Post, The New Republic, and The New Yorker. Hecht earned her Ph.D. in History from Columbia University in 1995 and now teaches in the graduate writing program of The New School University.