Dr. Lisette DePillis is the Norman F. Sprague Jr. Professor of Life Sciences, Professor of Mathematics, and Chair of the Department of Mathematics at Harvey Mudd College. Lisette is an applied mathematician. She creates mathematical models or structures to help describe questions in biology. In particular, Lisette has been working on building models to improve our understanding of diseases related to the human immune system, such as cancer. Her goal is to understand the genesis and dynamics of diseases as well as to discover improved and personalized treatment approaches. In her free time, Lisette plays piano, sings, dances, and reads for fun. She also enjoys spending time playing family games, visiting new places, going to movies, trying new restaurants, and going for walks outside with her husband and three daughters. They live up against the foothills in California, so they don’t have to walk far to be immersed in nature and see lots of wildlife. She received her PhD in mathematics from the University of California Los Angeles. Lisette was Director of the Harvey Mudd College Global Clinic Program prior to being elected department chair. Lisette has been recognized for her multidisciplinary research excellence with the Maria Goeppert-Mayer Distinguished Scholar Award from the Argonne National Laboratory. She is also a HERS-CBL Clare Boothe Luce Leadership in STEM Scholar and a Fellow of the American Mathematical Society. In our interview Lisette shared more about her life and work.