1) Seasonal prevalence of MS and 2) New Clinical Practice Journal. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. John Scagnelli interviews Dr. Dominik Meier about his paper on MS disease activity. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about drug-induced parkinsonism...and...alteplase-associated hemi?orolingual angioedema from the e-Pearl archives. In the next part of the podcast Dr. Ted Burns interviews Dr. John Corboy about the first issue of the new Clinical Practice Journal for our Lesson of the Week. The participants had nothing to disclose except Drs. Meier, Overman, Burns and Corboy. Dr. Meier has received research support from the NIH (R01 AG022092-01 [co investigator] and NCRR P41 RR013218 [consultant]. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Corboy serves as Editor for Clinical Practice Journal and Section Editor for Neurology Today, receives research support from Novartis [CFTY720D2309], the NIH [ NINDS1UO1NS4571901A1], and National MS Society and gave expert testimony in the trial of Colorado Anthony vs Loop, Morgan County District Court. A fixed 25 % of his salary is paid by the Rocky Mountain MS Center.