Vincent and Daniel solve the case of the Man in the City with Groin Rash, catch up on the long backlog of email, and present a new case, possibly the most complex one yet on the show. Hosts: Vincent Racaniello and Daniel Griffin Become a patron of TWiP. Links for this episode: Bloodless malaria diagnostic (BBC) Image credit Letters read on TWiP 154 Case Study for TWiP 154 Daniel's colleague will solve this case, in two weeks. 79 year old man history of chronic lymphocytic leukemia that became B cell lymphoma, had chemotherapy a few weeks before coming. Was discharged with scrip for prednisone, but pharmacy made error gave him enough to take every day for over two weeks. Patient has fevers up to 100 degrees at home, headache, develops dry nonproductive cough. Brought to ER by family, there reports has lost weight. No nausea, no vomiting, no abdominal pain or diarrhea. Admitted to hospital. Has fever, chest x-ray suggests pneumonia, started on ab. Fever and symptoms continue, stop steroids. Chest CT shows multifocal ground glass opacifications and nodules. Increase ab to broader spectrum, ID is consulted. Positive test for latent TB. History hypertension, coronary artery disease, enlarged prostate. Gets bactrim, antifungal, antiviral. Born in DR, living in US since 70s. Visits occasionally had been a few months before. Lives with wife, no pets, no smoking, no toxic habits. Heart rate in 90s, looking fatigued, coughing, scattered crackles in lung, old systolic murmur, no rashes, confused, but family says he is always like that. TB test is negative. Negative for strongyloides. WBC count has increased, 30% eosinophils (over 7000). Stool ONP ordered but becomes constipated. CAT scan of belly shows thickening of colon. Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees